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Acetylation of cyclophilin A is required for its secretion and vascular cell activation

AIMS: Cyclophilin A (CyPA) is a pro-inflammatory mediator involved in oxidative stress-related cardiovascular diseases. It is secreted from vascular smooth muscle cell (VSMC) in response to reactive oxygen species (ROS) in a highly regulated manner. Extracellular CyPA activates VSMCs and endothelial...

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Bibliografiske detaljer
Main Authors: Soe, Nwe Nwe, Sowden, Mark, Baskaran, Padmamalini, Kim, Yeonghwan, Nigro, Patrizia, Smolock, Elaine M., Berk, Bradford C.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928000/
https://ncbi.nlm.nih.gov/pubmed/24293519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt268
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