Nerve growth factor metabolic dysfunction in Down’s syndrome brains

Basal forebrain cholinergic neurons play a key role in cognition. This neuronal system is highly dependent on NGF for its synaptic integrity and the phenotypic maintenance of its cell bodies. Basal forebrain cholinergic neurons progressively degenerate in Alzheimer’s disease and Down’s syndrome, and...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Iulita, M. Florencia, Do Carmo, Sonia, Ower, Alison K., Fortress, Ashley M., Aguilar, Lisi Flores, Hanna, Michael, Wisniewski, Thomas, Granholm, Ann-Charlotte, Buhusi, Mona, Busciglio, Jorge, Cuello, A. Claudio
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927704/
https://ncbi.nlm.nih.gov/pubmed/24519975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awt372
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky