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The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains.

rho-like GTP binding proteins play an essential role in regulating cell growth and actin polymerization. These molecular switches are positively regulated by guanine nucleotide exchange factors (GEFs) that promote the exchange of GDP for GTP. Using the interaction-trap assay to identify candidate pr...

詳細記述

保存先:
書誌詳細
主要な著者: Debant, A, Serra-Pagès, C, Seipel, K, O'Brien, S, Tang, M, Park, S H, Streuli, M
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC39269/
https://ncbi.nlm.nih.gov/pubmed/8643598
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