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The critical role of the loops of triosephosphate isomerase for its oligomerization, dynamics, and functionality

Triosephosphate isomerase (TIM) catalyzes the reaction to convert dihydroxyacetone phosphate into glyceraldehyde 3-phosphate, and vice versa. In most organisms, its functional oligomeric state is a homodimer; however, tetramer formation in hyperthermophiles is required for functional activity. The t...

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Detalhes bibliográficos
Main Authors: Katebi, Ataur R, Jernigan, Robert L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926746/
https://ncbi.nlm.nih.gov/pubmed/24318986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2407
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