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The Role of Loop-Loop Interactions in Coordinating Motions and Enzymatic Function in Triosephosphate Isomerase
The enzyme triosephosphate isomerase (TIM) has been used as a model system for understanding the relationship between protein sequence, structure, and biological function. The sequence of the active site loop (loop 6) in TIM is directly correlated with a conserved motif in loop 7. Replacement of loo...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713366/ https://ncbi.nlm.nih.gov/pubmed/19348462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9002887 |
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