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Loop Motions of Triosephosphate Isomerase Observed with Elastic Networks

The internal dynamics of triosephosphate isomerase have been investigated with elastic networks, with and without a substrate bound. The slowest modes of motion involve large domain motions but also a loop motion that conforms to the changes observed between the crystal structures 8TIM and 1TPH. Our...

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Bibliografiske detaljer
Main Authors: Kurkcuoglu, Ozge, Jernigan, Robert L., Doruker, Pemra
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556966/
https://ncbi.nlm.nih.gov/pubmed/16430213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0518085
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