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Synthesis of A Photocaged Tamoxifen for Light-dependent Activation of Cre-ER Recombinase-driven Gene Modification

We report the design of a water-soluble, quaternized tamoxifen photoprobe and demonstrate its application for light-controlled induction of green fluorescent protein expression via a Cre-ER recombinase system.

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Detalhes bibliográficos
Main Authors: Inlay, Matthew A., Choe, Veronica, Bharathi, Sophia, Fernhoff, Nathaniel B., Baker, James R., Weissman, Irving L., Choi, Seok Ki
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926663/
https://ncbi.nlm.nih.gov/pubmed/23612712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc42179a
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