Nucleosomes associated with newly replicated DNA have an altered conformation

In vitro DNA synthesis was studied in HeLa cell nuclei, with emphasis on the question of whether newly replicated DNA is associated with nucleosomes. The newly replicated DNA was twice as sensitive to digestion by micrococcal nuclease as mature chromatin DNA, reaching a limit digest at 20-25% acid-i...

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Εκδόθηκε σε:	Proc Natl Acad Sci U S A
Κύριος συγγραφέας:	Seale, Ronald L.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	National Academy of Sciences 1978
Θέματα:	Biological Sciences: Biochemistry
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392634/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/275840/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.6.2717
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