Nucleosomes associated with newly replicated DNA have an altered conformation
In vitro DNA synthesis was studied in HeLa cell nuclei, with emphasis on the question of whether newly replicated DNA is associated with nucleosomes. The newly replicated DNA was twice as sensitive to digestion by micrococcal nuclease as mature chromatin DNA, reaching a limit digest at 20-25% acid-i...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1978
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392634/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/275840/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.6.2717 |
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