Nucleosomes associated with newly replicated DNA have an altered conformation
In vitro DNA synthesis was studied in HeLa cell nuclei, with emphasis on the question of whether newly replicated DNA is associated with nucleosomes. The newly replicated DNA was twice as sensitive to digestion by micrococcal nuclease as mature chromatin DNA, reaching a limit digest at 20-25% acid-i...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1978
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| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392634/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/275840/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.6.2717 |
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