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Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells

We have studied in detail the binding of fluorescent derivatives of insulin and epidermal growth factor to 3T3 fibroblasts. We have used two types of fluorescent analogues of insulin and epidermal growth factor: highly fluorescent derivatives which have seven to eight rhodamine molecules or fluoresc...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Schlessinger, Joseph, Shechter, Yoram, Willingham, Mark C., Pastan, Ira
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1978
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392622/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/307249/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.6.2659
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