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Modulation of binding and bioactivity of insulin by anti-insulin antibody: relation to possible role of receptor self-aggregation in hormone action.

Incubation of physiological concentrations of 125I-labeled insulin with liver membranes in the presence of anti-insulin IgG results in a 7- to 15-fold increase in the specific binding of the hormone. The low-affinity/high-capacity binding sites are replaced by an apparently homogeneous class of high...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Shechter, Y, Chang, K J, Jacobs, S, Cuatrecasas, P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1979
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383680/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/288060/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.6.2720
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