OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis

An immune response is essential for protection against infection, but, in many individuals, aberrant responses against self tissues cause autoimmune diseases such as rheumatoid arthritis (RA). How to diminish the autoimmune response while not augmenting infectious risk is a challenge. Modern targete...

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Autori principali: Gwyer Findlay, Emily, Danks, Lynett, Madden, Jodie, Cavanagh, Mary M., McNamee, Kay, McCann, Fiona, Snelgrove, Robert J., Shaw, Stevan, Feldmann, Marc, Taylor, Peter Charles, Horwood, Nicole J., Hussell, Tracy
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926072/
https://ncbi.nlm.nih.gov/pubmed/24469824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321071111
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