OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis

An immune response is essential for protection against infection, but, in many individuals, aberrant responses against self tissues cause autoimmune diseases such as rheumatoid arthritis (RA). How to diminish the autoimmune response while not augmenting infectious risk is a challenge. Modern targete...

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Detalhes bibliográficos
Main Authors: Gwyer Findlay, Emily, Danks, Lynett, Madden, Jodie, Cavanagh, Mary M., McNamee, Kay, McCann, Fiona, Snelgrove, Robert J., Shaw, Stevan, Feldmann, Marc, Taylor, Peter Charles, Horwood, Nicole J., Hussell, Tracy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926072/
https://ncbi.nlm.nih.gov/pubmed/24469824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321071111
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