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The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
Given the trillions of microbes that inhabit the mammalian intestines, the host immune system must constantly maintain a balance between tolerance to commensals and immunity against pathogens to avoid unnecessary immune responses against otherwise harmless bacteria. Misregulated responses can lead t...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3926023/ https://ncbi.nlm.nih.gov/pubmed/24390544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322269111 |
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