Global Inhibition of DC Priming Capacity in the Spleen of Self-Antigen Vaccinated Mice Requires IL-10

Dendritic cells (DC) in the spleen are highly activated following intravenous vaccination with a foreign-antigen, promoting expansion of effector T cells, but remain phenotypically and functionally immature after vaccination with a self-antigen. Up-regulation or suppression of expression of a cohort...

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Bibliographic Details
Main Authors: Marvel, Douglas M., Finn, Olivera J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925839/
https://ncbi.nlm.nih.gov/pubmed/24596571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00059
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