NK Cell IL-10 Production Requires IL-15 and IL-10 Driven STAT3 Activation

Natural killer (NK) cells can produce IFNγ or IL-10 to regulate inflammation and immune responses but the factors driving NK cell IL-10 secretion are poorly-defined. Here, we identified NK cell-intrinsic STAT3 activation as vital for IL-10 production during both systemic Listeria monocytogenes (Lm)...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Clark, Sarah E., Burrack, Kristina S., Jameson, Stephen C., Hamilton, Sara E., Lenz, Laurel L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736993/
https://ncbi.nlm.nih.gov/pubmed/31552035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02087
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