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Novel mechanisms underlying the immediate and transient global tolerization of splenic DC following vaccination with a self-Ag()

Dendritic cells (DC) are important orchestrators of the immune response, ensuring that immunity against pathogens is generated while immunity against healthy tissues is prevented. Using the tumor Ag MUC1, we previously showed that i.v. immunization of MUC1.Tg mice, but not WT, with a MUC1 peptide re...

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Detalhes bibliográficos
Main Authors: Farkas, Adam M., Finn, Olivera J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897305/
https://ncbi.nlm.nih.gov/pubmed/24337381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301904
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