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Novel mechanisms underlying the immediate and transient global tolerization of splenic DC following vaccination with a self-Ag()

Dendritic cells (DC) are important orchestrators of the immune response, ensuring that immunity against pathogens is generated while immunity against healthy tissues is prevented. Using the tumor Ag MUC1, we previously showed that i.v. immunization of MUC1.Tg mice, but not WT, with a MUC1 peptide re...

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Hlavní autoři: Farkas, Adam M., Finn, Olivera J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897305/
https://ncbi.nlm.nih.gov/pubmed/24337381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301904
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