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Tumor antigen epitopes interpreted by the immune system as self or abnormal-self differentially affect cancer vaccine responses

Epitope selection is an important consideration in the design of cancer vaccines, but factors impacting selection are not fully understood. We compared the immune response to peptides and glycopeptides from the common human tumor antigen MUC1, a mucin that is coated with O-linked carbohydrates in it...

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Detalhes bibliográficos
Main Authors: Ryan, Sean O., Turner, Michael S., Gariépy, Jean, Finn, Olivera J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905500/
https://ncbi.nlm.nih.gov/pubmed/20587526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4519
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