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Optimization of a self antigen for presentation of multiple epitopes in cancer immunity
T cells recognizing self antigens expressed by cancer cells are prevalent in the immune repertoire. However, activation of these autoreactive T cells is limited by weak signals that are incapable of fully priming naive T cells, creating a state of tolerance or ignorance. Even if T cell activation oc...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1435720/ https://ncbi.nlm.nih.gov/pubmed/16614758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25591 |
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