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Flagellin induces antibody responses through a TLR5- and inflammasome-independent pathway()
Flagellin is a potent immunogen that activates the innate immune system via TLR5 and Naip5/6, and generates strong T and B cell responses. The adaptor protein MyD88 is critical for signaling by TLR5, as well as IL-1 and IL-18 receptors, major downstream mediators of the Naip5/6 Nlrc4-inflammasome. H...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925749/ https://ncbi.nlm.nih.gov/pubmed/24442437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301893 |
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