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A conserved surface on Toll-like receptor 5 recognizes bacterial flagellin
The molecular basis for Toll-like receptor (TLR) recognition of microbial ligands is unknown. We demonstrate that mouse and human TLR5 discriminate between different flagellins, and we use this difference to map the flagellin recognition site on TLR5 to 228 amino acids of the extracellular domain. T...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118731/ https://ncbi.nlm.nih.gov/pubmed/17283206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061400 |
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