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Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation

Commensal and enteroinvasive microbes in the human gut release bacterial flagellin, a specific microbial ligand of Toll-like receptor 5 (TLR5). However, the pathophysiological role of bacterial flagellin in gastrointestinal inflammation has not been determined. Here we evaluated the role of bacteria...

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Detalhes bibliográficos
Main Authors: Rhee, Sang Hoon, Im, Eunok, Riegler, Martin, Kokkotou, Efi, O'Brien, Michael, Pothoulakis, Charalabos
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224619/
https://ncbi.nlm.nih.gov/pubmed/16157881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502174102
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