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Increased Robustness of Single-Molecule Counting with Microfluidics, Digital Isothermal Amplification, and a Mobile Phone versus Real-Time Kinetic Measurements

Quantitative bioanalytical measurements are commonly performed in a kinetic format, and are known to not be robust to perturbation that affects the kinetics itself, or the measurement of kinetics. We hypothesized that the same measurements performed in a “digital” (single-molecule) format would show...

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Main Authors: Selck, David A., Karymov, Mikhail A., Sun, Bing, Ismagilov, Rustem F.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924768/
https://ncbi.nlm.nih.gov/pubmed/24199852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac4030413
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