Reading Out Single-Molecule Digital RNA and DNA Isothermal Amplification in Nanoliter Volumes with Unmodified Camera Phones

[Image: see text] Digital single-molecule technologies are expanding diagnostic capabilities, enabling the ultrasensitive quantification of targets, such as viral load in HIV and hepatitis C infections, by directly counting single molecules. Replacing fluorescent readout with a robust visual readout...

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Pubblicato in:ACS Nano
Autori principali: Rodriguez-Manzano, Jesus, Karymov, Mikhail A., Begolo, Stefano, Selck, David A., Zhukov, Dmitriy V., Jue, Erik, Ismagilov, Rustem F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2016
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819493/
https://ncbi.nlm.nih.gov/pubmed/26900709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.5b07338
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