Human bronchus-mediated mutagenesis of mammalian cells by carcinogenic polynuclear aromatic hydrocarbons.

Cultured human bronchial explants activated benzo[alpha]pyrene (BzaP) into electrophilic metabolites that bind to DNA in bronchial epithelial cells. Promutagenic and mutagenic metabolites of BzaP were also released into the culture medium. An increase in mutation frequency for ouabain resistance was...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hsu, I C, Stoner, G D, Autrup, H, Trump, B F, Selkirk, J K, Harris, C C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1978
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392471/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/148049/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.4.2003
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!