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Observing a DNA Polymerase Choose Right from Wrong
DNA polymerase (pol) β is a model polymerase involved in gap-filling DNA synthesis utilizing two metals to facilitate nucleotidyl transfer. Previous structural studies have trapped catalytic intermediates by utilizing substrate analogues (dideoxy-terminated primer or non-hydrolysable incoming nucleo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3924593/ https://ncbi.nlm.nih.gov/pubmed/23827680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.05.048 |
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