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Osmotic pump tablets for delivery of antiretrovirals to the vaginal mucosa
Vaginal pre-exposure prophylaxis has focused heavily on gel formulations. Low adherence linked with frequent dosing and short therapeutic duration has emerged as the major reason for inconsistent efficacy outcomes with gels in clinical trials. Osmotic pumps can achieve versatile drug release profile...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3924427/ https://ncbi.nlm.nih.gov/pubmed/23973812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2013.08.007 |
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