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Osmotic pump tablets for delivery of antiretrovirals to the vaginal mucosa

Vaginal pre-exposure prophylaxis has focused heavily on gel formulations. Low adherence linked with frequent dosing and short therapeutic duration has emerged as the major reason for inconsistent efficacy outcomes with gels in clinical trials. Osmotic pumps can achieve versatile drug release profile...

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Hlavní autoři: Rastogi, Rachna, Teller, Ryan S., Mesquita, Pedro M. M., Herold, Betsy C., Kiser, Patrick F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924427/
https://ncbi.nlm.nih.gov/pubmed/23973812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2013.08.007
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