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Osmotic pump tablets for delivery of antiretrovirals to the vaginal mucosa

Vaginal pre-exposure prophylaxis has focused heavily on gel formulations. Low adherence linked with frequent dosing and short therapeutic duration has emerged as the major reason for inconsistent efficacy outcomes with gels in clinical trials. Osmotic pumps can achieve versatile drug release profile...

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Detalhes bibliográficos
Main Authors: Rastogi, Rachna, Teller, Ryan S., Mesquita, Pedro M. M., Herold, Betsy C., Kiser, Patrick F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924427/
https://ncbi.nlm.nih.gov/pubmed/23973812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2013.08.007
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