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Osmotic pump tablets for delivery of antiretrovirals to the vaginal mucosa

Vaginal pre-exposure prophylaxis has focused heavily on gel formulations. Low adherence linked with frequent dosing and short therapeutic duration has emerged as the major reason for inconsistent efficacy outcomes with gels in clinical trials. Osmotic pumps can achieve versatile drug release profile...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rastogi, Rachna, Teller, Ryan S., Mesquita, Pedro M. M., Herold, Betsy C., Kiser, Patrick F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924427/
https://ncbi.nlm.nih.gov/pubmed/23973812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2013.08.007
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