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Bcl-2 interrupts the ceramide-mediated pathway of cell death.

Ceramide, a product of sphingomyelin turn-over, has been proposed as a novel lipid second messenger with specific roles in mediating antiproliferative responses including apoptosis and cell cycle arrest. In this study, we examine the relationship between the ceramide-mediated pathway of growth suppr...

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Autori principali: Zhang, J, Alter, N, Reed, J C, Borner, C, Obeid, L M, Hannun, Y A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC39244/
https://ncbi.nlm.nih.gov/pubmed/8643573
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