Knee loading reduces MMP13 activity in the mouse cartilage

BACKGROUND: Moderate loads with knee loading enhance bone formation, but its effects on the maintenance of the knee are not well understood. In this study, we examined the effects of knee loading on the activity of matrix metalloproteinase13 (MMP13) and evaluated the role of p38 MAPK and Rac1 GTPase...

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Detalhes bibliográficos
Main Authors: Hamamura, Kazunori, Zhang, Ping, Zhao, Liming, Shim, Joon W, Chen, Andy, Dodge, Todd R, Wan, Qiaoqiao, Shih, Han, Na, Sungsoo, Lin, Chien-Chi, Sun, Hui Bin, Yokota, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924329/
https://ncbi.nlm.nih.gov/pubmed/24180431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-14-312
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