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Involvement of p38 MAPK in Regulation of MMP13 mRNA in Chondrocytes in Response to Surviving Stress to Endoplasmic Reticulum

MMP13 is enriched in mature chondrocytes and considered a prime cause of ECM degradation in the osteoarthritic articular cartilage in temporomandibular joints. We asked whether surviving stress to the endoplasmic reticulum (ER) would upregulate transcription of MMP13, and if so, whether a cross-talk...

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Detalhes bibliográficos
Main Authors: Hamamura, Kazunori, Goldring, Mary B., Yokota, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662326/
https://ncbi.nlm.nih.gov/pubmed/19100962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.archoralbio.2008.11.003
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