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Nucleotide Specificity of DNA Binding of the Aryl Hydrocarbon Receptor:ARNT Complex Is Unaffected by Ligand Structure

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxic and biological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin) and a wide variety of structurally diverse ligands through its ability to translocate into the nucleus and bind to a spe...

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Detalhes bibliográficos
Main Authors: DeGroot, Danica E., Denison, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924043/
https://ncbi.nlm.nih.gov/pubmed/24136190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft234
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