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Lack of Ligand-Selective Binding of the Aryl Hydrocarbon Receptor to Putative DNA Binding Sites Regulating Expression of Bax and Paraoxonase 1 Genes

The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that mediates the biological and toxicological effects of structurally diverse chemicals through its ability to bind specific DNA recognition sites (dioxin responsive elements (DREs)), and activate transcription of adjace...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DeGroot, Danica E., Hayashi, Ai, Denison, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875388/
https://ncbi.nlm.nih.gov/pubmed/24200861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2013.10.021
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