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Role of the Per/Arnt/Sim Domains in Ligand-dependent Transformation of the Aryl Hydrocarbon Receptor

The aryl hydrocarbon receptor (AhR) mediates the toxic and biological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds. In a process termed transformation, ligand binding converts the AhR into its high affinity DNA binding form that represents a dimer of the AhR and Arnt, a close...

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Detalhes bibliográficos
Main Authors: Soshilov, Anatoly, Denison, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583286/
https://ncbi.nlm.nih.gov/pubmed/18806268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802414200
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