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lncRNA recruits RNAi and the exosome to dynamically regulate pho1 expression in response to phosphate levels in fission yeast

Numerous noncoding transcripts of unknown function have recently been identified. In this study, we report a novel mechanism that relies on transcription of noncoding RNA prt (pho1-repressing transcript) regulating expression of the pho1 gene. A product of this gene, Pho1, is a major secreted phosph...

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Detalhes bibliográficos
Main Authors: Shah, Sneha, Wittmann, Sina, Kilchert, Cornelia, Vasiljeva, Lidia
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923966/
https://ncbi.nlm.nih.gov/pubmed/24493644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.230177.113
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