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Bases of antisense lncRNA-associated regulation of gene expression in fission yeast.

Antisense (as)lncRNAs can regulate gene expression but the underlying mechanisms and the different cofactors involved remain unclear. Using Native Elongating Transcript sequencing, here we show that stabilization of antisense Exo2-sensitivite lncRNAs (XUTs) results in the attenuation, at the nascent...

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Autors principals: Maxime Wery, Camille Gautier, Marc Descrimes, Mayuko Yoda, Valérie Migeot, Damien Hermand, Antonin Morillon
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2018-07-01
Col·lecció:PLoS Genetics
Accés en línia:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1007465&type=printable
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