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lncRNA recruits RNAi and the exosome to dynamically regulate pho1 expression in response to phosphate levels in fission yeast

Numerous noncoding transcripts of unknown function have recently been identified. In this study, we report a novel mechanism that relies on transcription of noncoding RNA prt (pho1-repressing transcript) regulating expression of the pho1 gene. A product of this gene, Pho1, is a major secreted phosph...

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Autori principali: Shah, Sneha, Wittmann, Sina, Kilchert, Cornelia, Vasiljeva, Lidia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923966/
https://ncbi.nlm.nih.gov/pubmed/24493644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.230177.113
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