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Crystal Structure of Mycoplasma arthritidis Mitogen Complexed with HLA-DR1 Reveals a Novel Superantigen Fold and a Dimerized Superantigen-MHC Complex
Mycoplasma arthritidis -derived mitogen (MAM) is a superantigen that can activate large fractions of T cells bearing particular TCR Vβ elements. Here we report the crystal structure of MAM complexed with a major histocompatibility complex (MHC) antigen, HLA-DR1, loaded with haemagglutinin peptide 30...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3923524/ https://ncbi.nlm.nih.gov/pubmed/14962388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2004.01.008 |
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