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Crystal structure of the Mycoplasma arthritidis-derived mitogen in apo form reveals a 3D domain-swapped dimer

Mycoplasma arthritidis -derived mitogen (MAM) is a superantigen (SAg) that can activate large fractions of T cells bearing particular Vβ elements of T-cell receptor (TCR). Here we report the crystal structure of a MAM mutant K201A in apo form (unliganded) at 2.8Å resolutions. We also partially refin...

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Detalhes bibliográficos
Main Authors: Liu, Lihui, Li, Zhong, Guo, Yi, VanVranken, Sandra J., Mourad, Walid, Li, Hongmin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916022/
https://ncbi.nlm.nih.gov/pubmed/20417218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.04.030
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