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Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC
‘Superantigens’ (SAgs) trigger the massive activation of T cells by simultaneous interactions with MHC and TCR receptors, leading to human diseases. Here we present the first crystal structure, at 2.5-Å resolution, of a complete ternary complex between a SAg and its two receptors, HLA-DR1/HA and TCR...
Tallennettuna:
| Päätekijät: | , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2007
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3923521/ https://ncbi.nlm.nih.gov/pubmed/17220897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1193 |
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