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Accounting for population variation in targeted proteomics

Individual proteomes typically differ from the reference human proteome at ~10,000 single amino acid variants. When viewed at the population scale, this individual variation results in a wide variety of protein sequences. In targeted proteomics experiments, such variability can confound accurate pro...

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Detalhes bibliográficos
Main Authors: Fujimoto, Grant M, Monroe, Matthew E, Rodriguez, Larissa, Wu, Chaochao, MacLean, Brendan, Smith, Richard D, MacCoss, Michael J, Payne, Samuel H
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923399/
https://ncbi.nlm.nih.gov/pubmed/24320210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr4011052
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