The human cap-binding complex is functionally connected to the nuclear RNA exosome

Nuclear processing and quality control of eukaryotic RNA is mediated by the RNA exosome, which is regulated by accessory factors. However, the mechanism of exosome recruitment to its ribonucleoprotein (RNP) targets remains poorly understood. Here we disclose a physical link between the human exosome...

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Detalhes bibliográficos
Main Authors: Andersen, Peter Refsing, Domanski, Michal, Kristiansen, Maiken S., Storvall, Helena, Ntini, Evgenia, Verheggen, Celine, Schein, Aleks, Bunkenborg, Jakob, Poser, Ina, Hallais, Marie, Sandberg, Rickard, Hyman, Anthony, LaCava, John, Rout, Michael P., Andersen, Jens S., Bertrand, Edouard, Jensen, Torben Heick
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923317/
https://ncbi.nlm.nih.gov/pubmed/24270879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2703
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