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Mutagenesis, biochemical, and biophysical characterization of Mycoplasma arthritidis-derived mitogen

Mycoplasma arthritidis -derived mitogen (MAM) is a superantigen (SAg) that can activate large fractions of T cells bearing particular TCR Vβ elements. Here we report the mutagenesis, biochemical and biophysical studies on the dimerization of MAM in solution. Our studies showed that although MAM main...

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Autori principali: Li, Hongmin, Zhao, Yiwei, Guo, Yi, VanVranken, Sandra J., Li, Zhong, Eisele, Leslie, Mourad, Walid
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923304/
https://ncbi.nlm.nih.gov/pubmed/16753217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2006.04.010
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