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Genome-scale reconstruction of the sigma factor network in Escherichia coli: topology and functional states

BACKGROUND: At the beginning of the transcription process, the RNA polymerase (RNAP) core enzyme requires a σ-factor to recognize the genomic location at which the process initiates. Although the crucial role of σ-factors has long been appreciated and characterized for many individual promoters, we...

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Autores principales: Cho, Byung-Kwan, Kim, Donghyuk, Knight, Eric M, Zengler, Karsten, Palsson, Bernhard O
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923258/
https://ncbi.nlm.nih.gov/pubmed/24461193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-12-4
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