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Synergistic enhancement of NK cell-mediated cytotoxicity by combination of histone deacetylase inhibitor and ionizing radiation

BACKGROUND: The overexpression of histone deacetylase (HDAC) and a subsequent decrease in the acetylation levels of nuclear histones are frequently observed in cancer cells. Generally it was accepted that the deacetylation of histones suppressed expression of the attached genes. Therefore, it has be...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Son, Cheol-Hun, Keum, Jin-Hee, Yang, Kwangmo, Nam, Jiho, Kim, Mi-Ju, Kim, Sun-Hee, Kang, Chi-Dug, Oh, Sae-Ock, Kim, Chi-Dae, Park, You-Soo, Bae, Jaeho
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923253/
https://ncbi.nlm.nih.gov/pubmed/24512718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-9-49
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