Synergistic enhancement of NK cell-mediated cytotoxicity by combination of histone deacetylase inhibitor and ionizing radiation

BACKGROUND: The overexpression of histone deacetylase (HDAC) and a subsequent decrease in the acetylation levels of nuclear histones are frequently observed in cancer cells. Generally it was accepted that the deacetylation of histones suppressed expression of the attached genes. Therefore, it has be...

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Detalhes bibliográficos
Main Authors: Son, Cheol-Hun, Keum, Jin-Hee, Yang, Kwangmo, Nam, Jiho, Kim, Mi-Ju, Kim, Sun-Hee, Kang, Chi-Dug, Oh, Sae-Ock, Kim, Chi-Dae, Park, You-Soo, Bae, Jaeho
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923253/
https://ncbi.nlm.nih.gov/pubmed/24512718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-9-49
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