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Structural basis of stereospecific reduction by quinuclidinone reductase
Chiral molecule (R)-3-quinuclidinol, a valuable compound for the production of various pharmaceuticals, is efficiently synthesized from 3-quinuclidinone by using NADPH-dependent 3-quinuclidinone reductase (RrQR) from Rhodotorula rubra. Here, we report the crystal structure of RrQR and the structure-...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3922912/ https://ncbi.nlm.nih.gov/pubmed/24507746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-0855-4-6 |
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