Expression, purification, crystallization and X-ray analysis of 3-quinuclidinone reductase from Agrobacterium tumefaciens

(R)-3-Quinuclidinol is a useful chiral building block for the synthesis of various pharmaceuticals and can be produced from 3-quinuclidinone by asymmetric reduction. A novel 3-quinuclidinone reductase from Agrobacterium tumefaciens (AtQR) catalyzes the stereospecific reduction of 3-quinuclidinone to...

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Bibliographic Details
Main Authors: Hou, Feng, Miyakawa, Takuya, Takeshita, Daijiro, Kataoka, Michihiko, Uzura, Atsuko, Nagata, Koji, Shimizu, Sakayu, Tanokura, Masaru
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2012
Subjects:
Crystallization Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497986/
https://ncbi.nlm.nih.gov/pubmed/23027756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112034951
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