Characterization of a Novel Glucokinase Activator in Rat and Mouse Models

Glucokinase (GK) is a hexokinase isozyme that catalyzes the phosphorylation of glucose to glucose-6-phosphate. Glucokinase activators are being investigated as potential diabetes therapies because of their effects on hepatic glucose output and/or insulin secretion. Here, we have examined the efficac...

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Detalhes bibliográficos
Main Authors: Lu, Min, Li, Pingping, Bandyopadhyay, Gautam, Lagakos, William, DeWolf, Walter E., Alford, Taylor, Chicarelli, Mark Joseph, Williams, Lance, Anderson, Deborah A., Baer, Brian R., McVean, Maralee, Conn, Marion, Véniant, Murielle M., Coward, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922816/
https://ncbi.nlm.nih.gov/pubmed/24533087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088431
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